Applied Pharmaceutical Structural Bioinformatics

Duration: Flexible 10 weeks

Location for Studies: Flexible (On-site Preferred)

Fee: ₹ 5000

Outline of the course: The course is given through on-site instructions, down-loadable documents, audio-visual self-studies and teacher-supervised exercises that student solves on computer using available software. The course has no fixed timing and the student can carry out their duties at any time of each study week. This course on Applied Pharmaceutical Structural Bioinformatics intends to teach how to solve practical problems in pharmacology, life sciences and bioinformatics of your molecule of interest using free software and databases relating to the structure of functional proteins and drug targets. The course covers bioinformatics for nucleotide and amino acid sequences and structural bioinformatics. This includes methods, databases and software for analysis and management of amino acid and nucleotide sequences, secondary and tertiary structures of proteins, methods and tools for homology modeling of protein 3D structure, and molecular dynamics simulations and molecular docking. The focus of the course is on practical exercises where the student solves biophysical structural problem. Besides theoretical teachings, course contains the following practical sections:

• Data base searching
• Pairwise and multiple sequence alignments
• Prediction of secondary protein structure
• Prediction of protein 3D structure
• 3D Structure Visualization (PyMol)
• Validation of 3D structures
• Molecular dynamic simulation
• Molecular docking and drug screening (computer-aided drug design)
• Generate publication quality images and videos
• Build a web page that shows your study research report
• Compile and submit your results to a journal for publication

Teacher: Dr Manish Chandra Pathak

email: pmc@Gyankatta.Org

Phone / WhatsApp: 
+91-9424476571